李孟森合作者关系

Molecular Analysis of AFP and HSA Interactions with PTEN Protein.

作者：Zhu, MY (Zhu, Mingyue);Lin, B (Lin, Bo);Zhou, P (Zhou, Peng);Li, MS (Li, Mengsen) （1 College of Agriculture, Hainan University, Haikou, Hainan 570228, China 2 Hainan Provincial Key Laboratory of Carcinogenesis and Intervention, Hainan Medical College, Haikou, Hainan 571199, China 3 Key Laboratory of Molecular Biology, Hainan Medical College, Haikou, Hainan 571199, China 4 Institution of Tumor, Hainan Medical College, Haikou, Hainan 570102, China）

出处：Biomed Res Int 2015

摘要：Human cytoplasmic alpha-fetoprotein (AFP) has been classified as a member of the albuminoid gene family. The protein sequence of AFP has significant h ...

Alpha-fetoprotein triggers hepatoma cells escaping from immune surveillance through altering the expression of Fas/FasL and tumor necrosis factor related apoptosis-inducing ligand and its receptor of 文摘 CA CSCD

作者：Li MS，Ma QL，Chen Q，Liu XH，Li PF，Du GG，Li G （Department of Biochemistry，Hainan Medical College，Haikou 571101，HainanProvince，China）

出处：世界胃肠病学杂志(英文版) 2005

Mechanisms involved in phosphatidylinositol 3-kinase pathway mediated up-regulation of the mu opioid receptor in lymphocytes

作者：Han Liu;Hui Li;Liyuan Guo;Mengsen Li;Chaoying Li;Shanshan Wang;Wei Jiang;Xinhua Liu;Michael A. McNutt;Gang Li （b Department of Pathology, Peking University Health Science Center, Peking University, Beijing 100083, China a Department of Biochemistry and Molecular Biology, Peking University Health Science Center, Peking University, Beijing 100083, China c Key Laboratory of Molecular Biology, Hainan Medical College, Haikou 570102, China）

出处：Biochemical Pharmacology 2010

关键词： Morphine;Mu;opioid;receptor;PI3K;Signaling;Gene;expression;Regulation

摘要：Despite the substantial progress made in understanding initiation expression of the MOR gene in lymphocytes, the signal pathway associated with MOR ge ...

Alpha-fetoprotein Triggers Hepatoma Cells Escaping from Immune Surveillance through Altering the Expression of Fas/fasl and Tumor Necrosis Factor Related Apoptosis-inducing Ligand and its Receptor of Lymphocytes and Liver Cancer Cells.

作者：Li MS;Ma QL;Chen Q;Liu XH;Li PF;Du GG;Li G. （Department of Biochemistry, Hainan Medical College, Haikou, China. mengsenli@163.com）

出处：World Journal of Gastroenterology 2005

关键词： Hepatoma;Cells;Immune;Surveillance;Tumor;Necrosis;Factor;Apoptosis Inducing;Ligands;Alpha fetoproteins;Liver;Cancer;Cells

摘要：AIM: To investigate the mechanism of alpha-fetoprotein (AFP) in escaping from the host immune surveillance of hepatoc-ellular carcinoma. METHODS: AFP ...

α-Fetoprotein shields hepatocellular carcinoma cells from apoptosis induced by tumor necrosis factor-related apoptosis-inducing ligand

作者：Mengsen Li;Sheng Zhou;Xinhua Liu;Pingfeng Li;Michael A. McNutt;Gang Li （1 Department of Biochemistry and Molecular Biology, Peking University Health Science Center, Beijing 100083, China 2 Laboratory of Analysis Chemistry, Hainan Medical College, Hainan 571101, China 3 Department of Pathology, Peking University Health Science Center, Beijing 100083, China 4 Center of Infectious Disease, Peking University, Beijing 100083, China）

出处：Cancer Letters 2006

关键词： α fetoprotein;Tumor;necrosis;factor related;apoptosis inducing;ligand;Apoptosis;Caspase 3

摘要：The interference of α-fetoprotein (AFP) with the apoptosis induced by tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) in Bel 7402 cell ...

甲胎蛋白与Caspase信号轴分子的选择性识别及其抗凋亡诱导的作用机制

作者：李孟森，谢协驹，郭峻莉，朱明月，李伟，龙儒桃，鲁琰

关键词：甲胎蛋白；肝癌；细胞信号传递

摘要：成果研究结果显示,AFP能选择性结合caspase-3活性,抑制caspase-3传递凋亡信号,这是高表达AFP的肝癌细胞耐受TRAIL 诱导凋亡的一个重要因素,而且还发现AFP能与PTEN结合,通过抑制PTEN 的作用,激活PI3K/AKT的信号传递,促进肝癌细胞生长,对抗生物药物和化学药物诱导的 ...

RelA乙酰化对病毒性肝癌细胞耐受TRATL的影响及其机制

作者：李伟，李孟森，朱明月，王小英，王咸寿，高新征

关键词：肝癌；RelA；TRAIL

摘要：肿瘤坏死因子相关凋亡诱导配体(TNF related apoptosis inducing ligand,TRAIL)能够诱导肿瘤细胞凋亡,对正常组织和细胞没有明显的毒副作用,是一个非常有开发前景的治疗肿瘤的细胞因子。多种肝癌细胞系对TRAIL都不敏感,肝癌(hepatocellular carci ...

甲胎蛋白对人肝癌Bel 7402细胞caspase信号传递及耐受TRAIL的影响

作者：李孟森，詹志农，周升，刘新华，李刚（海南医学院分子生物学重点实验室;北京大学医学部生物化学与分子生物学系;海南医学院检验医学系;）（海南医学院分子生物学重点实验室;北京大学医学部生物化学与分子生物学系;海南医学院检验医学系;）

出处：西安交通大学学报(医学版) 2009

关键词：甲胎蛋白肿瘤坏死因子相关凋亡诱导配体肿瘤耐药肝癌细胞 caspase信息通路

摘要：目的研究甲胎蛋白(AFP)对人肝癌Bel 7402细胞内caspase信息通路信号传递的影响,以及对肿瘤坏死因子相关凋亡诱导配体(TRAIL)诱导肝癌细胞凋亡的对抗作用。方法激光共聚焦显微镜观察AFP与caspase-3、caspase-8在Bel 7402细胞内的共定位;免疫共沉淀(Co-IP)技 ...

被引情况：超星被引 1 次

螺旋CT血管造影对复杂主动脉瘤支架置入前的指导价值核源 CSCD

作者：聂忠仕，李传资，肖占祥，李孟森（海南省农垦总医院放射科；海南省人民医院血管外科；海南医学院分子生物学重点实验室）

出处：临床放射学杂志 2010

关键词：计算机体层摄影术血管造影术主动脉瘤支架

摘要：目的探讨64层螺旋CT血管造影对复杂主动脉瘤支架置入前的指导价值。资料与方法 9例复杂主动脉瘤患者支架置入前行64层螺旋CT血管造影。结果根据64层螺旋CT血管造影测量数据进行手术方案及支架模型的设计,除1例出现少许内瘘仍在随访外,其余8例均达到了预期的效果。结论 64层螺旋CT血管造影对复杂主动脉 ...

被引情况：超星被引 1 次

曲古抑菌素A增加人肝癌Bel7402细胞对TRAIL的敏感性

作者：李伟，朱明月，董栩，夏华，陈栘，鲁琰，谢协驹，符史干，李孟森（海南医学院肿瘤发生和干预重点实验室；海南医学院分子生物学重点实验室；海南医学院病理生理学教研室；海南医学院；海南医学院生理学教研室；海南医学院肿瘤研究所）（海南医学院肿瘤发生和干预重点实验室；海南医学院分子生物学重点实验室；海南医学院病理生理学教研室；海南医学院；海南医学院生理学教研室；海南医学院肿瘤研究所）

出处：第六届海南省生命科学联合学术会议 2014

关键词：肝癌细胞曲古抑菌素A 肿瘤坏死因子相关凋亡诱导配体细胞凋亡

摘要：目的探讨曲古抑菌素A(Trichostatin A,TSA)联合肿瘤坏死因子相关凋亡诱导配体(TNF related apoptosis inducing ligand,TRAIL)对肝癌细胞Bel7402增殖凋亡的影响,并初步探讨其可能机制。方法采用3-(4,5-二甲基噻唑-2)-2,5-二苯基四 ...